Victoria's TAC is urging the state's motorists to take greater care on the road, with recent figures showing a six percent increase in the overall incidence of road trauma.
This figure is from the 12 months leading up to October 2011, but constitutes a similar spike over the five year average.
Among these most recent figures, drivers aged 21-25 were reflected worst with a 16 percent increase in serious injuries.
Drivers aged 60-69 were similarly highlighted, with a 14 percent increase over the same period.
The TAC defines serious injury as any that requires acute hospital admission within seven days of an incident.
A total of 5,721 serious injuries occurred on Victorian roads over this period, compared to 5,410 the year prior, with a five year average of 5,570.
"These latest figures are a reminder that the road toll is not only about the tragic deaths, but also the thousands of people who are seriously injured on our roads each year,” TAC CEO Janet Dore said.
"All of us in the community need to take responsibility for helping reduce the road toll."
Regions with the highest incidence of road trauma included Casey (244), Geelong (231), Melbourne (226), Greater Dandenong (216), and Yarra Ranges (199).